| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1375728 | Bioorganic & Medicinal Chemistry Letters | 2005 | 4 Pages |
Abstract
In an effort to generate novel anti-osteoporosis agents, new bisphosphonates with various benzoyl groups on side chains have been synthesized and evaluated for activities on both bone resorption and bone formation in vitro. Several candidates showed distinct dual activities: promoting bone formation and inhibiting bone resorption.
Graphical abstractA novel series of bisphosphonates with activities both on bone resorption and formation have been synthesized.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yuli Xie, Huasheng Ding, Lihui Qian, Xueming Yan, Chunhao Yang, Yuyuan Xie,