| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1375781 | Bioorganic & Medicinal Chemistry Letters | 2008 | 4 Pages |
Abstract
SAR around alkyne–quinuclidine derivatives allowed the discovery of highly potent muscarinic antagonists displaying interesting preferential slow off-rates from the M3 receptor.
Graphical abstractSAR around alkyne–quinuclidine derivatives allowed the discovery of highly potent muscarinic antagonists displaying interesting preferential slow off-rates from the M3 receptor.Figure optionsDownload full-size imageDownload as PowerPoint slide
Keywords
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jean-Philippe Starck, Laurent Provins, Bernard Christophe, Michel Gillard, Sophie Jadot, Patrick Lo Brutto, Luc Quéré, Patrice Talaga, Michel Guyaux,