Article ID Journal Published Year Pages File Type
1375846 Bioorganic & Medicinal Chemistry Letters 2009 4 Pages PDF
Abstract

Two series of 1,3,4-oxadiazoline heterocycle derivatives were designed, synthesized and identified. Bioactivity assays showed that all synthesized compounds inhibited chitin synthesis in yeast, suggesting they might be a novel class of potential inhibitors against chitin biosynthesis. The structure–activity relationships (SAR) of these compounds are discussed.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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