Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1375846 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
Two series of 1,3,4-oxadiazoline heterocycle derivatives were designed, synthesized and identified. Bioactivity assays showed that all synthesized compounds inhibited chitin synthesis in yeast, suggesting they might be a novel class of potential inhibitors against chitin biosynthesis. The structure–activity relationships (SAR) of these compounds are discussed.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Shaoyong Ke, Fengyi Liu, Ni Wang, Qing Yang, Xuhong Qian,