| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1375909 | Bioorganic & Medicinal Chemistry Letters | 2009 | 5 Pages |
Abstract
A series of α-amidosulfones were found to be potent and selective agonists of CB2. The discovery, synthesis, and structure–activity relationships of this series of agonists are reported. In addition, the pharmacokinetic properties of the most promising compounds are profiled.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Isaac E. Marx, Erin F. DiMauro, Alan Cheng, Renee Emkey, Stephen A. Hitchcock, Liyue Huang, Ming Y. Huang, Jason Human, Josie H. Lee, Xingwen Li, Matthew W. Martin, Ryan D. White, Robert T. Fremeau Jr., Vinod F. Patel,