| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1375999 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
A series of proline based melanocortin ligands has been developed on the basis of initial piperazine leads by using a more conformationally rigid scaffold. A number of these novel ligands showed significant binding affinity for MC3 and MC4 receptors.
Graphical abstractA series of proline based melanocortin ligands has been developed on the basis of initial piperazine leads by using a more conformationally rigid scaffold. A number of these novel ligands showed significant binding affinity for MC3 and MC4 receptors.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
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Chemistry
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Authors
Xinrong Tian, Timothy Field, Adam W. Mazur, Frank H. Ebetino, John A. Wos, Doreen Crossdoersen, Beth B. Pinney, Russell J. Sheldon,