| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1376017 | Bioorganic & Medicinal Chemistry Letters | 2005 | 4 Pages |
Abstract
We describe the synthesis and evaluation of three new competitive inhibitors of triose-phosphate isomerase. One of them (phosphoglycoloamidoxime: Ki = 4.5 μM) is among the best reversible inhibitors so far reported for this enzyme.
Graphical abstractWe describe the synthesis and evaluation of three new competitive inhibitors of triose-phosphate isomerase. One of them (phosphoglycoloamidoxime 3a: Ki = 4.5 μM) is among the best reversible inhibitors so far reported for this enzyme.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
M. Fonvielle, S. Mariano, M. Therisod,