| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1376018 | Bioorganic & Medicinal Chemistry Letters | 2005 | 4 Pages |
Abstract
A series of 3-phenyl-3H-quinazolin-4-ones have been synthesized and tested for affinity and activity at the chemokine CXCR3 receptor. The most potent compound (1d) has been evaluated using radioligand binding and calcium mobilization assays and is considered a useful tool for further characterization of the CXCR3 receptor.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Stefania Storelli, Pauline Verdijk, Dennis Verzijl, Henk Timmerman, Andrea C. van de Stolpe, Cornelis P. Tensen, Martine J. Smit, Iwan J.P. De Esch, Rob Leurs,