Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1376054 | Bioorganic & Medicinal Chemistry Letters | 2007 | 4 Pages |
Abstract
Based upon observations from our initial findings, additional myxopyronin B analogs have been prepared and tested for in vitro inhibitory activity against DNA-dependent RNA polymerase and antibacterial activity against Escherichia coli and Staphylococcus aureus.
Graphical abstractNovel myxopyronin B analogs have been prepared and tested for in vitro inhibitory activity against DNA-dependent RNA polymerase and antibacterial activity against Escherichia coli and Staphylococcus aureus.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ricardo Lira, Alan X. Xiang, Thomas Doundoulakis, William T. Biller, Konstantinos A. Agrios, Klaus B. Simonsen, Stephen E. Webber, Wes Sisson, Robert M. Aust, Amit M. Shah, Richard E. Showalter, Virginia N. Banh, Kevin R. Steffy, James R. Appleman,