| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1376075 | Bioorganic & Medicinal Chemistry Letters | 2007 | 6 Pages |
Abstract
A 1000-member uridinyl branched peptide library was synthesized on PS-DES support using IRORI technology. High-throughput screening of this library for anti-tuberculosis activity identified several members with a MIC90 value of 12.5 μg/mL.
Graphical abstractSolid-phase synthesis and biological evaluation of a uridinyl branched peptide urea library 1 as Mureidomycin mimetics are described.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
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Authors
Dianqing Sun, Victoria Jones, Elizabeth I. Carson, Robin E.B. Lee, Michael S. Scherman, Michael R. McNeil, Richard E. Lee,