| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1376127 | Bioorganic & Medicinal Chemistry Letters | 2008 | 4 Pages |
Abstract
Hydrolysis of DNA is of increasing importance in biotechnology and medicine. In this Letter, we present the DNA-cleavage potential of metal-free hydroxylamines and oximes as new members of nucleic acid cleavage agents.
Graphical abstractHydrolysis of DNA is of increasing importance in biotechnology and medicine. In this Letter, we present the DNA-cleavage potential of metal-free hydroxylamines and oximes as new members of nucleic acid cleavage agents.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Luciano Fernandes, Franciele L. Fischer, Carolina W. Ribeiro, Gustavo P. Silveira, Marcus M. Sá, Faruk Nome, Hernán Terenzi,