| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1376168 | Bioorganic & Medicinal Chemistry Letters | 2008 | 5 Pages |
Abstract
A series of Incentrom A analogs that inhibit the chromosome segregation process in yeast were synthesized and tested for their effects on chromosome stability and cell proliferation. Pharmacophore and structure–activity relationship of Incentrom A for the anti-yeast activity were established.
Graphical abstractPharmacophore and structure–activity relationship of Incentrom A that inhibits the chromosome segregation process in yeast were established. A series of Incentrom A analogs were synthesized and tested for the anti-yeast activity.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hee-Yoon Lee, Yongsik Jung, Wonyeob Kim, Jin Hee Kim, Min-Soo Suh, Seung Koo Shin, Hye-Joo Yoon,