| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1376175 | Bioorganic & Medicinal Chemistry Letters | 2008 | 5 Pages |
Abstract
The SAR and pharmacokinetic profiles of a series of multi-isoform PI3K inhibitors based on a 3,4-dihydro-2H-benzo[1,4]oxazine scaffold are disclosed.
Graphical abstractThe SAR and pharmacokinetic profiles of a series of multi-isoform PI3K inhibitors based on a 3,4-dihydro-2H-benzo[1,4]oxazine scaffold are disclosed.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Achieving multi-isoform PI3K inhibition in a series of substituted 3,4-dihydro-2H-benzo[1,4]oxazines](/preview/png/1376175.png "First Page Preview: Achieving multi-isoform PI3K inhibition in a series of substituted 3,4-dihydro-2H-benzo[1,4]oxazines")
Authors
Benjamin Perry, Rikki Alexander, Gavin Bennett, George Buckley, Tom Ceska, Tom Crabbe, Verity Dale, Lewis Gowers, Helen Horsley, Lynwen James, Kerry Jenkins, Karen Crépy, Claire Kulisa, Helen Lightfoot, Chris Lock, Stephen Mack, Trevor Morgan,