| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1376182 | Bioorganic & Medicinal Chemistry Letters | 2008 | 5 Pages |
Abstract
A new method for solid phase parallel synthesis of chemically and conformationally diverse macrocyclic peptidomimetics is reported. A key feature of the method is access to broad chemical and conformational diversity. Synthesis and mechanistic studies on the macrocyclization step are reported.
Graphical abstractA new method for solid phase parallel synthesis of chemically and conformationally diverse macrocyclic peptidomimetics is reported.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Eric Marsault, Hamid R. Hoveyda, René Gagnon, Mark L. Peterson, Martin Vézina, Carl Saint-Louis, Annick Landry, Jean-François Pinault, Luc Ouellet, Sophie Beauchemin, Sylvie Beaubien, Axel Mathieu, Kamel Benakli, Zhigang Wang, Martin Brassard,