| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1376227 | Bioorganic & Medicinal Chemistry Letters | 2008 | 5 Pages |
Abstract
We designed and synthesized a series of novel 3,6-bicyclolide oximes, possessing linkers of varying lengths to the secondary binding site. The E isomers exhibited excellent antibacterial profiles against a broad spectrum of resistant pathogens.
Graphical abstractWe designed and synthesized a series of novel 3,6-bicyclolide oximes, possessing linkers of varying lengths to the secondary binding site. The E isomers exhibited excellent antibacterial profiles against a broad spectrum of resistant pathogens.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Datong Tang, Yonghua Gai, Alexander Polemeropoulos, Zhigang Chen, Zhe Wang, Yat Sun Or,