| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1376409 | Bioorganic & Medicinal Chemistry Letters | 2008 | 4 Pages |
Abstract
An efficient synthesis of a series of carbosilane dendrimers uniformly functionalized with sialyl α(2 → 3) lactose (Neu5Acα(2 → 3)Galβ(1 → 4)Glcβ1→) moieties was accomplished. The results of a preliminary study on biological responses against influenza virus hemagglutinin, using the sialyl lactose clusters showed unique biological activities on the basis of the structure–activity relationship according to the carbosilane scaffolds.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hiroyuki Oka, Tomotsune Onaga, Tetsuo Koyama, Chao-Tan Guo, Yasuo Suzuki, Yasuaki Esumi, Ken Hatano, Daiyo Terunuma, Koji Matsuoka,