| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1376410 | Bioorganic & Medicinal Chemistry Letters | 2008 | 4 Pages |
Abstract
Abstract-Reaction of 6a–f individually with 2-methylsulfonyl-4,6-dimethoxypyrimidine yielded 7a–f in excellent yield. The newly synthesized heterocycles were characterized by IR, 1H NMR, and mass spectral data. Compounds 7a–f was screened for their anti-inflammatory activity and were compared with standard drugs. Of the compounds studied, the compound 7e showed more potent activity than the standard drugs at all doses tested.
Graphical abstractThe newly synthesized compounds 2-(2-aroylaroxy)-4,6-dimethoxy pyrimidines 7a–f were screened for their anti-inflammatory activity and compared with standard drugs.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
T.D. Venu, S.A. Khanum, Aiysha Firdouse, B.K. Manuprasad, Sheena Shashikanth, Riyaz Mohamed, Bannikuppe Sannanaik Vishwanth,