Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1376417 | Bioorganic & Medicinal Chemistry Letters | 2008 | 4 Pages |
Abstract
This study reports the identification and Hits to Leads optimization of inhibitors of coactivator associated arginine methyltransferase (CARM1). Compound 7b is a potent, selective inhibitor of CARM1.
Graphical abstractThis study reports the identification and Hits to Leads optimization of inhibitors of coactivator associated arginine methyltransferase (CARM1). Compound 7b is a potent, selective inhibitor of CARM1.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ashok V. Purandare, Zhong Chen, Tram Huynh, Suhong Pang, Jieping Geng, Wayne Vaccaro, Michael A. Poss, Jonathan Oconnell, Kimberly Nowak, Lata Jayaraman,