| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1376513 | Bioorganic & Medicinal Chemistry Letters | 2006 | 6 Pages |
Abstract
A new class of pyrimidine-based Janus tyrosine kinase 3 (JAK3) inhibitors are described. Many of these inhibitors showed low nanomolar activity against JAK3.
Graphical abstractA new class of pyrimidine-based Janus tyrosine kinase 3 (JAK3) inhibitors are described. Many of these inhibitors showed low nanomolar activity against JAK3.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jack J. Chen, Kumar D. Thakur, Michael P. Clark, Steven K. Laughlin, Kelly M. George, Roger G. Bookland, Jan R. Davis, Edward J. Cabrera, Vijay Easwaran, Biswanath De, Y. George Zhang,