| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1376518 | Bioorganic & Medicinal Chemistry Letters | 2006 | 5 Pages |
Abstract
A new immobilization chemistry for covalent attachment of phosphorylated oligonucleotides on epoxy-activated glass surface via opening of oxirane ring is described. The proposed strategy results in excellent immobilization efficiency, spot homogeneity, and morphology. The constructed microarray was successfully demonstrated for discrimination of nucleotide mismatches.
Graphical abstractAn efficient and facile method for covalent attachment of phosphorylated oligonucleotides on epoxy-activated glass surface is described.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
S. Mahajan, P. Kumar, K.C. Gupta,