| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1376526 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
The synthesis and biological evaluation of a series of benzimidazolone β3 adrenergic receptor agonists are described. A trend toward the reduction of rat atrial tachycardia upon increasing steric bulk at the 3-position of the benzimidazolone moiety was observed.
Graphical abstractThe synthesis and biological evaluation of a series of benzimidazolone β3 adrenergic receptor agonists are described. A trend toward the reduction of rat atrial tachycardia upon increasing steric bulk at the 3-position of the benzimidazolone moiety was observed.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Don R. Finley, Michael G. Bell, Anthony G. Borel, William E. Bloomquist, Marlene L. Cohen, Mark. L. Heiman, Aidas Kriauciunas, Donald P. Matthews, Tania Miles, David A. Neel, Christopher J. Rito, Daniel J. Sall, Anthony J. Shuker, Thomas W. Stephens,