Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1376538 | Bioorganic & Medicinal Chemistry Letters | 2008 | 5 Pages |
Abstract
A series of bis-anilinopyrimidines have been identified as potent inhibitors of the tyrosine kinase EphB4. Structural information from two alternative series identified from screening efforts was combined to identify the initial leads.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Catherine Bardelle, Darren Cross, Sara Davenport, Jason G. Kettle, Eun Jung Ko, Andrew G. Leach, Andrew Mortlock, Jon Read, Nicola J. Roberts, Peter Robins, Emma J. Williams,