Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1376612 | Bioorganic & Medicinal Chemistry Letters | 2008 | 6 Pages |
Abstract
Discovery of a series of tert-butyl pyrrolidine derived, potent and orally bioavailable melanocortin receptor subtype-4 (MC4R) selective modulators is disclosed.
Graphical abstractDiscovery of a series of tert-butyl pyrrolidine derived, potent and orally bioavailable melanocortin receptor subtype-4 (MC4R) selective modulators is disclosed.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Liangqin Guo, Zhixiong Ye, Feroze Ujjainwalla, Heather L. Sings, Iyassu K. Sebhat, John Huber, David H. Weinberg, Rui Tang, Tanya MacNeil, Constantin Tamvakopoulos, Qianping Peng, Euan MacIntyre, Lex H.T. van der Ploeg, Mark T. Goulet,