| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1376756 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
A new 24-membered ring lactone, macrolactin N, was isolated from a culture broth of Bacillus subtilis and its structure was established by various spectral analysis. Macrolactin N inhibited Staphylococcus aureus peptide deformylase with an IC50 value of 7.5 μM and also showed antibacterial activity against Escherichia coli and S. aureus.
Graphical abstractA new 24-membered ring lactone, macrolactin N, was isolated from a culture broth of Bacillus subtilis and its structure was established by various spectral analysis. Macrolactin N inhibited Staphylococcus aureus peptide deformylase with an IC50 value of 7.5 μM.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jung-Sung Yoo, Chang-Ji Zheng, Sangku Lee, Jin-Hwan Kwak, Won-Gon Kim,