| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1376785 | Bioorganic & Medicinal Chemistry Letters | 2008 | 6 Pages |
Abstract
The synthesis and the structure activity of a new series of pyrrolo[1,2-a]pyrazine is reported. These molecules are potent and selective non-competitive mGluR5 antagonists and may shed new light on the pattern of substitution tolerated by this receptor.
Graphical abstractThe synthesis of a new class of potent and selective mGluR5 antagonists are reported.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
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Authors
Fabrizio Micheli, Barbara Bertani, Andrea Bozzoli, Luca Crippa, Paolo Cavanni, Romano Di Fabio, Daniele Donati, Paola Marzorati, Giancarlo Merlo, Alfredo Paio, Lorenzo Perugini, Paola Zarantonello,