| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1376793 | Bioorganic & Medicinal Chemistry Letters | 2008 | 4 Pages |
Abstract
The urine of canines given daily dosage of pyridoxamine revealed an unidentified metabolite hypothesized to be N-methylpyridoxamine. Its identity was established by synthesis of N-methylpyridoxamine and comparison to the canine metabolite by HPLC. The synthetic compound was confirmed by IR, NMR, UV-vis, and emission spectroscopy. Although N-methylpyridoxamine is a significant canine pyridoxamine metabolite, relevance to vitamin B6 metabolism in other species, including humans, is not yet determined.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Karen L. Ericson, Vincent M. Maloney, J. Dennis Mahuren, Stephen P. Coburn, Thorsten P. Degenhardt,