Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1376834 | Bioorganic & Medicinal Chemistry Letters | 2008 | 7 Pages |
Abstract
Chalcone derivatives of the natural product khellinone were synthesised and screened for bioactivity against the voltage-gated potassium channel Kv1.3. X-ray crystallography was employed to investigate relationships between the structure and function of a selection of the reported chalcones.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Julia Cianci, Jonathan B. Baell, Bernard L. Flynn, Robert, W. Gable, Jorgen A. Mould, Dharam Paul, Andrew J. Harvey,