Article ID Journal Published Year Pages File Type
1376838 Bioorganic & Medicinal Chemistry Letters 2008 5 Pages PDF
Abstract

A series of constrained pentapeptide analogues of the fragment Aβ31–35 has been prepared using solid phase synthesis protocols. The results of conformational studies and surface plasmon resonance (SPR) experiments seem to indicate that the affinity of these constrained analogues for immobilized Aβ25–35 peptide could be related to their ability to adopt a Leu34N-Ile31O β-turn-like folded conformation.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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