| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1376853 | Bioorganic & Medicinal Chemistry Letters | 2008 | 5 Pages |
Abstract
Potent small molecule antagonists for the PAC1-R have been discovered. Previously known antagonists for the PAC1-R were slightly truncated peptide ligands. The hydrazides reported here are the first small molecule antagonists ever reported for this class B GPCR.
Graphical abstractPotent small molecule antagonists for the PAC1-R have been discovered. Previously known antagonists for the PAC1-R were slightly truncated peptide ligands. The hydrazides reported here are the first small molecule antagonists ever reported for this class B GPCR.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Xenia Beebe, Daria Darczak, Rachel A. Davis-Taber, Marie E. Uchic, Victoria E. Scott, Michael F. Jarvis, Andrew O. Stewart,