| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1376980 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
We report the design, synthesis, and binding affinities of a family of cyclic RGD peptides attached to type VI β-turn scaffolds. The analogues prepared exhibit interesting binding data to the isolated receptors αvβ3 and αvβ5. The results demonstrate the utility of these type VI β-turn scaffolds for the constraint of biologically relevant peptides.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Christopher J. Creighton, Yanming Du, Rosemary J. Santulli, Brett A. Tounge, Allen B. Reitz,