Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1377109 | Bioorganic & Medicinal Chemistry Letters | 2008 | 5 Pages |
Abstract
Potent and selective A3 adenosine receptor (AR) full antagonists with a nucleoside skeleton, of which the affinity and selectivity are independent of species, were discovered. Steric factors in the 5â² region were important in binding of nucleosides to the human A3AR.
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Authors
Lak Shin Jeong, Hyuk Woo Lee, Hea Ok Kim, Dilip K. Tosh, Shantanu Pal, Won Jun Choi, Zhan-Guo Gao, Amit R. Patel, Wanda Williams, Kenneth A. Jacobson, Hee-Doo Kim,