| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1377127 | Bioorganic & Medicinal Chemistry Letters | 2008 | 4 Pages |
Abstract
A set of closely related furylidene thiosemicarbazones was prepared and screened against various clinically important Gram-positive bacteria. One compound containing an ethylene spacer and a 5-nitrofuryl group was found to have promising activity against Clostridium difficile.
Graphical abstractThe synthesis and screening of a set of antimicrobial thiosemicarbazones is reported.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Cait Costello, Tarja Karpanen, Peter A. Lambert, Preena Mistry, Katy J. Parker, Daniel L. Rathbone, Jiangmeng Ren, Laura Wheeldon, Tony Worthington,