| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1377131 | Bioorganic & Medicinal Chemistry Letters | 2008 | 5 Pages |
Abstract
A high-throughput screening campaign resulted in the discovery of a highly potent dual cannabinoid receptor 1 (CB1) and 2 (CB2) agonist. Following a thorough SAR exploration, a series of selective CB2 full agonists were identified.
Graphical abstractA high-throughput screening campaign resulted in the discovery of a highly potent dual cannabinoid receptor 1 (CB1) and 2 (CB2) agonist. Following a thorough SAR exploration, a series of selective CB2 full agonists were identified.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
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Authors
Monika Ermann, Doris Riether, Edward R. Walker, Innocent F. Mushi, James E. Jenkins, Beatriz Noya-Marino, Mark L. Brewer, Malcolm G. Taylor, Patricia Amouzegh, Stephen P. East, Brian W. Dymock, Mark J. Gemkow, Andreas F. Kahrs, Andreas Ebneth,