Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1377142 | Bioorganic & Medicinal Chemistry Letters | 2007 | 5 Pages |
Abstract
A new fluorescent peptide probe for the detection of Zn2+ was synthesized on the basis of zinc binding ligands in zinc enzymes. The peptide that has a unique amino acid sequence displayed a great selectivity for Zn2+ in the presence of several transition metal ions in aqueous solution. The reversibility, binding stoichiometry, binding affinity, and pH sensitivity of the sensor were studied. Further, on-bead application of the peptide as chemosensors was demonstrated.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Bishnu Prasad Joshi, Won-Mi Cho, Jongseung Kim, Juyoung Yoon, Keun-Hyeung Lee,