Article ID Journal Published Year Pages File Type
1377142 Bioorganic & Medicinal Chemistry Letters 2007 5 Pages PDF
Abstract

A new fluorescent peptide probe for the detection of Zn2+ was synthesized on the basis of zinc binding ligands in zinc enzymes. The peptide that has a unique amino acid sequence displayed a great selectivity for Zn2+ in the presence of several transition metal ions in aqueous solution. The reversibility, binding stoichiometry, binding affinity, and pH sensitivity of the sensor were studied. Further, on-bead application of the peptide as chemosensors was demonstrated.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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