Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1377148 | Bioorganic & Medicinal Chemistry Letters | 2007 | 4 Pages |
Abstract
Pd-catalyzed aminocarbonylation between aryl bromide and NH-benzazepinone was effectively carried out to furnish the key intermediate for tolvaptan (up to 85%) in one step.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yasuhiro Torisawa, Takuya Furuta, Takao Nishi, Shinji Aki, Jun-ichi Minamikawa,