| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1377174 | Bioorganic & Medicinal Chemistry Letters | 2007 | 4 Pages |
Abstract
High throughput screening combined with efficient datamining and parallel synthesis led to the discovery of a novel series of indolines showing potent in vitro ghrelin receptor agonist activity and acceleration of gastric emptying in rats.
Graphical abstractA series of indolines showing potent in vitro ghrelin receptor agonism and acceleration of gastric emptying in rats is described.Figure optionsDownload full-size imageDownload as PowerPoint slide
Keywords
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Tom D. Heightman, Jackie S. Scott, Mark Longley, Vincent Bordas, David K. Dean, Richard Elliott, Gail Hutley, Jason Witherington, Lee Abberley, Barry Passingham, Manuela Berlanga, Maite de los Frailes, Alan Wise, Ben Powney, Alison Muir, Fiona McKay,