Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1377186 | Bioorganic & Medicinal Chemistry Letters | 2007 | 4 Pages |
Abstract
Eight d-ribo-phytosphingosine derivatives were synthesized from d-ribo-phytosphingosine and diverse acyl chlorides with N,N-diisopropylethylamine in tetrahydrofuran for 1Â h at room temperature. Effect of these compounds on IR-induced cell death was evaluated on blood cancer cells (Jurkat). Among these, 3d showed the highest enhancement of radiosensitizing effect.
Related Topics
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Authors
Byung Seok Moon, Moon-Taek Park, Jeong Hoon Park, Sang Wook Kim, Kyo Chul Lee, Gwang Il An, Seung Dae Yang, Dae Yoon Chi, Gi Jeong Cheon, Su-Jae Lee,