Article ID Journal Published Year Pages File Type
1377186 Bioorganic & Medicinal Chemistry Letters 2007 4 Pages PDF
Abstract
Eight d-ribo-phytosphingosine derivatives were synthesized from d-ribo-phytosphingosine and diverse acyl chlorides with N,N-diisopropylethylamine in tetrahydrofuran for 1 h at room temperature. Effect of these compounds on IR-induced cell death was evaluated on blood cancer cells (Jurkat). Among these, 3d showed the highest enhancement of radiosensitizing effect.
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Physical Sciences and Engineering Chemistry Organic Chemistry
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