| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1377205 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
Glycidyl esters upon treatment with a mixture of carboxylic acid anhydride (CAA) and trimethylsilyl halide (TMSX) in the presence of tetra-n-butylammonium halide (Bu4NX, X = Cl, Br or I) undergo stereospecific and regioselective opening of the oxirane ring to afford mixed-(or mono)-acid 1,2(2,3)-diacyl-3(1)-halo-sn-glycerols in high yields.
Graphical abstractEfficient synthesis of diacyl-halo-sn-glycerols is reported.Figure optionsDownload full-size imageDownload as PowerPoint slide
Keywords
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Stephan D. Stamatov, Jacek Stawinski,