Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1377234 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
The synthesis and evaluation of several chemical modulators of heat shock protein 90 (Hsp90) dimerization is presented. These agents may represent useful tools to study the importance of N-terminal dimerization and also to determine subunit interface(s) in Hsp90.
Graphical abstractThe synthesis and evaluation of several Hsp90 chemical modulators is reported.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Gabriela Chiosis, Julia Aguirre, Christopher V. Nicchitta,