| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1377336 | Bioorganic & Medicinal Chemistry Letters | 2008 | 4 Pages |
Abstract
Imidazo[4,5-c]quinoline derivatives have been discovered and developed as potent and effective modulators of the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) pathway to lead to clinical development candidates. The SAR data of representative examples of this compound class and their biological profiling in cellular and in vivo settings are presented and discussed.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
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Authors
Frédéric Stauffer, Sauveur-Michel Maira, Pascal Furet, Carlos García-Echeverría,