| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1377357 | Bioorganic & Medicinal Chemistry Letters | 2008 | 4 Pages |
Abstract
A series of 3,4,5-trisubstituted 1,2,4-4H triazole derivatives was synthesized and investigated for HIV-1 reverse transcriptase inhibition. An X-ray structure with HIV-1 RT secured the binding mode and allowed the key interactions with the enzyme to be identified.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Thorsten A. Kirschberg, Mini Balakrishnan, Wei Huang, Rebecca Hluhanich, Nilima Kutty, Albert C. Liclican, Damian J. McColl, Neil H. Squires, Eric B. Lansdon,