| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1377468 | Bioorganic & Medicinal Chemistry Letters | 2006 | 5 Pages |
Abstract
This paper reports the synthesis of new chlorin–polyamine conjugates designed to improve the targeting of cancer cells. Photocytotoxic activity of these photosensitizers was tested against human chronic myelogenous leukemia cells (K562) and compared to the effects of Photofrin II® and chlorin e6.
Graphical abstractBiological tests were realized on K562 cells.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Guillaume Garcia, Vincent Sol, François Lamarche, Robert Granet, Michel Guilloton, Yves Champavier, Pierre Krausz,