Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1377472 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
The synthesis of the metabolite of a potent 3-aminopyrazole CDK2/cyclin A inhibitor is presented. The use of polymer-supported cyanoborohydride in trifluoroethanol proved most convenient in the reductive amination step.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Marcella Nesi, Daniela Borghi, Maria Gabriella Brasca, Francesco Fiorentini, Paolo Pevarello,