| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1377474 | Bioorganic & Medicinal Chemistry Letters | 2006 | 6 Pages |
Abstract
Novel, potent farnesoid X receptor (FXR) and peroxisome proliferator-activated receptor α (PPARα) agonists were obtained by using a diphenylmethane skeleton as a substitute for a steroid skeleton.
Graphical abstractDesign and preparation of novel ligands for FXR, DPPF-01, and for PPARα, DPHK-01, were described.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Masahiko Kainuma, Jun-ichi Kasuga, Shinnosuke Hosoda, Ken-ichi Wakabayashi, Aya Tanatani, Kazuo Nagasawa, Hiroyuki Miyachi, Makoto Makishima, Yuichi Hashimoto,