Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1377540 | Bioorganic & Medicinal Chemistry Letters | 2007 | 4 Pages |
Abstract
An improved procedure for solid phase coupling of Boc-aminooxyacetic acid to peptides is described. By avoiding base-containing activation mixtures which cause over-acylation, it practically suppresses this unwanted side reaction and leads to near quantitative yields of Aoa-peptides, useful as glycoprobe precursors in glycomic studies.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Carmen Jiménez-Castells, Beatriz G. de la Torre, Ricardo Gutiérrez Gallego, David Andreu,