Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1377557 | Bioorganic & Medicinal Chemistry Letters | 2007 | 6 Pages |
Abstract
A series of novel indene N-oxide derivatives were prepared by various synthetic methods and evaluated for their ability to activate PPARγ. The best PPARγ agonist in this series was 9 h, which showed an EC50 value of 15 nM.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jin Hee Ahn, Mi Sik Shin, Sun Ho Jung, Jin Ah Kim, Hye Min Kim, Se Hoan Kim, Seung Kyu Kang, Kwang Rok Kim, Sang Dal Rhee, Sung Dae Park, Jae Mok Lee, Jeong Hyung Lee, Hyae Gyeong Cheon, Sung Soo Kim,