| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1377576 | Bioorganic & Medicinal Chemistry Letters | 2007 | 4 Pages |
Abstract
The synthesis and in vitro binding of several new arginine-containing C3aR ligands are reported. DMPK properties and functional activities of selected compounds have been evaluated. One compound is shown to be active in an in vivo model of airway inflammation after aerosol administration.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Frédéric Denonne, Sophie Binet, Maggi Burton, Philippe Collart, Alan Dipesa, Tanmoy Ganguly, Alexander Giannaras, Seema Kumar, Timothy Lewis, Florence Maounis, Jean-Marie Nicolas, Tamsin Mansley, Patrick Pasau, Dorin Preda, Karin Stebbins,