| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1377616 | Bioorganic & Medicinal Chemistry Letters | 2007 | 5 Pages |
Abstract
The development of a series of novel aminopyrimidines as inhibitors of c-Jun N-terminal kinases is described. The synthesis, in vitro inhibitory values for JNK1, JNK2 and CDK2, and the in vitro inhibitory value for a c-Jun cellular assay are discussed.
Graphical abstractA series of novel aminopyrimidines is reported which exhibits JNK1 and JNK2 inhibitory activity.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mahbub Alam, Rebekah E. Beevers, Tom Ceska, Richard J. Davenport, Karen M. Dickson, Mara Fortunato, Lewis Gowers, Alan F. Haughan, Lynwen A. James, Mark W. Jones, Natasha Kinsella, Christopher Lowe, Johannes W.G. Meissner, Anne-Lise Nicolas,