Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1377619 | Bioorganic & Medicinal Chemistry Letters | 2007 | 6 Pages |
Abstract
The synthesis of a series of unnatural aeruginosin hybrids and their structure-activity relationships against thrombin are reported. The d-3R-chloroleucine hybrid 16 was found as one of the most active thrombin inhibitors in this series.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Stephen Hanessian, Karolina Ersmark, Xiaotian Wang, Juan R. Del Valle, Niklas Blomberg, Yafeng Xue, Ola Fjellström,