| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1377621 | Bioorganic & Medicinal Chemistry Letters | 2007 | 6 Pages |
Abstract
A number of RXR modulators with novel structural features were synthesized and screened in the functional assays. The synthesis and the structure–activity relationship within the series of compounds will be presented. Some in vivo data generated in the models for dyslipidemia and diabetes will also be presented.
Graphical abstractA number of RXR modulators with novel structural features were synthesized and screened in the functional assays. The synthesis and the structure–activity relationship within the series of compounds will be presented. Some in vivo data generated in the models for dyslipidemia and diabetes will also be presented.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Dihydro-[1H]-quinolin-2-ones as retinoid X receptor (RXR) agonists for potential treatment of dyslipidemia](/preview/png/1377621.png "First Page Preview: Dihydro-[1H]-quinolin-2-ones as retinoid X receptor (RXR) agonists for potential treatment of dyslipidemia")
Authors
Bharat Lagu, Rimma Lebedev, Barbara Pio, Maria Yang, Patricia D. Pelton,