| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1377648 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
Oxindole (2) is a potent and selective PDE2 inhibitor with a favorable ADME, physiochemical and pharmacokinetic profile to allow for use as a chemical tool in elucidating the physiological role of PDE2.
Graphical abstractOxindole (2) is a potent and selective PDE2 inhibitor with a favorable ADME, physiochemical and pharmacokinetic profile to allow for use as a chemical tool in elucidating the physiological role of PDE2.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Robert J. Chambers, Kristin Abrams, Norman Y. Garceau, Ajith V. Kamath, Christopher M. Manley, Susan C. Lilley, Douglas A. Otte, Dennis O. Scott, Alissa L. Sheils, David A. Tess, A. Samuel Vellekoop, Yan Zhang, Kelvin T. Lam,